Helynck, G. : rechercher sur Z-Library

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1

Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus

Frechet, D., Guitton, J. D., Herman, F., Faucher, D., Helynck, G., Monegier du Sorbier, B., Ridoux, J. P., James-Surcouf, E., Vuilhorgne, M.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1003 KB

english, 1994

2

Isolation of RP 71955, a new anti-HIV-1 peptide secondary metabolite.

HELYNCK, GERARD, DUBERTRET, CATHERINE, MAYAUX, JEAN-FRANCOIS, LEBOUL, JEAN

Journal:

The Journal of Antibiotics

Année:

1993

Langue:

english

Fichier:

PDF, 135 KB

english, 1993

3

ChemInform Abstract: Isolation of RP 66453, a New Secondary Peptide Metabolite from Streptomyces sp. Useful as a Lead for Neurotensin Antagonists.

G. HELYNCK, C. DUBERTRET, D. FRECHET, J. LEBOUL

Journal:

Année:

1998

Fichier:

PDF, 28 KB

1998

4

Arbovirus infections and viral haemorrhagic fevers in Uganda: a serological survey in Karamoja district, 1984

F. Rodhain, J.P. Gonzalez, E. Mercier, B. Helynck, B. Larouze, C. Hannoun

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Année:

1989

Langue:

english

Fichier:

PDF, 430 KB

english, 1989

5

Intrinsic fluorescence of a non-myelin apoproteolipid and evidence for the existence of conformational flexibility

Béatrice Lux, Gérard Helynck, Elisabeth Trifilieff, Bang Luu, Dominique Gerard

Journal:

Biophysical Chemistry

Année:

1984

Langue:

english

Fichier:

PDF, 695 KB

english, 1984

6

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

Sara Van Poecke, Hélène Munier-Lehmann, Olivier Helynck, Matheus Froeyen, Serge Van Calenbergh

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 556 KB

english, 2011

7

Brain Proteolipids : Isolation, Purification and Effect on Ionic Permeability of Membranes

Gérard HELYNCK, Bang LUU, Jean-Louis NUSSBAUM, Douglas PICKEN, Georges SKALIDIS, Elisabeth TRIFILIEFF, Alain Van DORSSELAER, Patrick SETA, Roger SANDEAUX, Claude GAVACH, Frédéric HEITZ, Daniel SIMON,

Journal:

Année:

1983

Langue:

english

Fichier:

PDF, 719 KB

english, 1983

8

Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products

Courtois, S., Cappellano, C. M., Ball, M., Francou, F.-X., Normand, P., Helynck, G., Martinez, A., Kolvek, S. J., Hopke, J., Osburne, M. S., August, P. R., Nalin, R., Guerineau, M., Jeannin, P., Simon

Journal:

Applied and Environmental Microbiology

Année:

2003

Langue:

english

Fichier:

PDF, 305 KB

english, 2003

9

Tuberculose vertebrale au burkina Faso : A propos de 45 observations

Prazuck, T., Simonnet, F., Helynck, B., Malkin, J.E.

Journal:

Médecine et Maladies Infectieuses

Année:

1989

Fichier:

PDF, 284 KB

1989

10

Purification and characterization of minor brain proteolipids: use of fast atom bombardment — mass spectrometry for peptide sequencing

Lepage, Pierre, Helynck, Gérard, Chu, Ji-Yu, Luu, Bang, Sorokine, Odile, Trifilieff, Elisabeth, van Dorsselaer, Alain

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1986

11

Perception et usage de la cigarette électronique et du tabac dans une population étudiante, enquête IDEA 2014

Isnard, H., Helynck, B., Crépey, P.

Journal:

Revue d'Épidémiologie et de Santé Publique

Année:

2014

Langue:

french

Fichier:

PDF, 443 KB

french, 2014

12

Original 2-(3-Alkoxy-1 H -pyrazol-1-yl)pyrimidine Derivatives as Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

Munier-Lehmann, Hélène, Lucas-Hourani, Marianne, Guillou, Sandrine, Helynck, Olivier, Zanghi, Gigliola, Noel, Anne, Tangy, Frédéric, Vidalain, Pierre-Olivier, Janin, Yves L.

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 790 KB

english, 2015

13

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

Zeidler, U., Bougnoux, M.-E., Lupan, A., Helynck, O., Doyen, A., Garcia, Z., Sertour, N., Clavaud, C., Munier-Lehmann, H., Saveanu, C., d'Enfert, C.

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2013

Langue:

english

Fichier:

PDF, 536 KB

english, 2013

14

Atypical Chikungunya virus infections: clinical manifestations, mortality and risk factors for severe disease during the 2005–2006 outbreak on Réunion

ECONOMOPOULOU, A., DOMINGUEZ, M., HELYNCK, B., SISSOKO, D., WICHMANN, O., QUENEL, P., GERMONNEAU, P., QUATRESOUS, I.

Journal:

Epidemiology and Infection

Année:

2009

Langue:

english

Fichier:

PDF, 106 KB

english, 2009

15

Original 2-(3-Alkoxy-1 H -pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

Lucas-Hourani, Marianne, Munier-Lehmann, Hélène, El Mazouni, Farah, Malmquist, Nicholas A., Harpon, Jane, Coutant, Eloi P., Guillou, Sandrine, Helynck, Olivier, Noel, Anne, Scherf, Artur, Phillips, Ma

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2015

16

High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery

Aulner, Nathalie, Danckaert, Anne, Rouault-Hardoin, Eline, Desrivot, Julie, Helynck, Olivier, Commere, Pierre-Henri, Munier-Lehmann, Hélène, Späth, Gerald F., Shorte, Spencer L., Milon, Geneviève, Pri

Journal:

PLoS Neglected Tropical Diseases

Année:

2013

Langue:

english

Fichier:

PDF, 5.47 MB

english, 2013

17

Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity

Lucas-Hourani, Marianne, Dauzonne, Daniel, Jorda, Pierre, Cousin, GaÃ«lle, Lupan, Alexandru, Helynck, Olivier, Caignard, GrÃ©gory, Janvier, GeneviÃ¨ve, AndrÃ©-Leroux, GwÃ©naÃ«lle, Khiar, Samira, Escri

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 6.29 MB

english, 2013

18

Toxicity of a novel antifungal compound is modulated by ERAD components

Raj, Shriya, Krishnan, Karthik, Askew, David S., Helynck, Olivier, Suzanne, Peggy, Lesnard, Aureslien, Rault, Sylvain, Zeidler, Ute, d'Enfert, Christophe, Latgé, Jean-Paul, Munier-Lehmann, Hélène, Sav

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2015

19

Atypical Chikungunya Virus Infections: Clinical Manifestations, Mortality and Risk Factors for Severe Disease during the 2005-2006 Outbreak on Réunion

A. Economopoulou, M. Dominguez, B. Helynck, D. Sissoko, O. Wichmann, P. Quenel, P. Germonneau and I. Quatresous

Journal:

Epidemiology and Infection

Année:

2009

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2009

20

HIV seroprevalence rates in Benin

Adjovi, C., Josse, R., Foundohou, J., Helynck, B., Davo, N.

Journal:

Année:

1994

Fichier:

PDF, 145 KB

1994

21

Isolation of RP 66453, a New Secondary Peptide Metabolite from Streptomyces sp. Useful as a Lead for Neurotensin Antagonists.

HELYNCK, GERARD, DUBERTRET, CATHERINE, FRECHET, DENISE, LEBOUL, JEAN

Journal:

The Journal of Antibiotics

Année:

1998

Langue:

english

Fichier:

PDF, 328 KB

english, 1998

22

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Lucas-Hourani, Marianne, Munier-Lehmann, Hélène, Helynck, Olivier, Komarova, Anastassia, Desprès, Philippe, Tangy, Frédéric, Vidalain, Pierre-Olivier

Journal:

Journal of Visualized Experiments

Année:

2014

Langue:

english

Fichier:

PDF, 930 KB

english, 2014

23

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Khiar, Samira, Lucas-Hourani, Marianne, Nisole, Sébastien, Smith, Nikaïa, Helynck, Olivier, Bourgine, Maryline, Ruffié, Claude, Herbeuval, Jean-Philippe, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidal

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 3.05 MB

english, 2017

24

An original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response

Lucas-Hourani, Marianne, Dauzonne, Daniel, Munier-Lehmann, Hélène, Khiar, Samira, Nisole, Sébastien, Dairou, Julien, Helynck, Olivier, Afonso, Philippe V., Tangy, Frédéric, Vidalain, Pierre-Olivier

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 6.08 MB

english, 2017

25

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

Buchieri, Maria V., Cimino, Mena, Rebollo-Ramirez, Sonia, Beauvineau, Claire, Cascioferro, Alessandro, Favre-Rochex, Sandrine, Helynck, Olivier, Naud-Martin, Delphine, Larrouy-Maumus, Gerald, Munier-L

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2017

26

A novel polyaminocarboxylate compound to treat murine pulmonary aspergillosis by interfering with zinc metabolism

Laskaris, Paris, Vicentefranqueira, Rocío, Helynck, Olivier, Jouvion, Grégory, Calera, José Antonio, du Merle, Laurence, Suzenet, Franck, Buron, Frédéric, Alves de Sousa, Rodolphe, Mansuy, Daniel, Cav

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 2.50 MB

english, 2018

27

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

Dabo, Stephanie, Maillard, Patrick, Collados Rodriguez, Milagros, Hansen, Marianne Doré, Mazouz, Sabrina, Bigot, Donna-Joe, Tible, Marion, Janvier, Geneviève, Helynck, Olivier, Cassonnet, Patricia, Ja

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2017

28

Activation de la réponse innée antivirale par des inhibiteurs de la biosynthèse des pyrimidines

Vidalain, Pierre-Olivier, Lucas-Hourani, Marianne, Helynck, Olivier, Tangy, Frédéric, Munier-Lehmann, Hélène

Journal:

médecine/sciences

Année:

2015

Fichier:

PDF, 1.58 MB

2015

29

First-in-class allosteric inhibitors of bacterial IMPDHs

Alexandre, Thomas, Lupan, Alexandru, Helynck, Olivier, Vichier-Guerre, Sophie, Dugué, Laurence, Gelin, Muriel, Haouz, Ahmed, Labesse, Gilles, Munier-Lehmann, Hélène

Journal:

European Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 3.00 MB

english, 2019

30

Proposal of a Noninvasive Method to Reduce Injection-Related Bruising in Aesthetic Medicine: Transillumination

La Padula, Simone, Hersant, Barbara, Helynck, Patrick, Mezi SidAhmed, Mounia, Meningaud, Jean Paul

Journal:

Aesthetic Plastic Surgery

Année:

2019

Langue:

english

Fichier:

PDF, 308 KB

english, 2019

31

Proposal of a Noninvasive Method to Reduce Injection-Related Bruising in Aesthetic Medicine: Transillumination

La Padula, Simone, Hersant, Barbara, Helynck, Patrick, Mezi SidAhmed, Mounia, Meningaud, Jean Paul

Journal:

Aesthetic Plastic Surgery

Année:

2019

Fichier:

PDF, 308 KB

2019